A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 9/00 (2006.01) A61K 31/43 (2006.01) A61K 31/545 (2006.01) A61K 31/546 (2006.01) A61K 31/7048 (2006.01) A61K 31/716 (2006.01)
Patent
CA 2505298
Methods and materials useful for applying pharmacologic agents to the ear are described. The methods involve delivering a composition that contains at least one viscogenic agent and at least one pharmacologic agent to the epidermal surface of the tympanic membrane via the ear canal. The composition is delivered to the tympanic membrane in a flowable form and, after delivery to the tympanic membrane, becomes sufficiently viscous such that the pharmacologic agent is localized against the tympanic membrane. Such compositions can be used to prophylactically and/or therapeutically treat middle and inner ear conditions, including otitis media.
L'invention concerne des procédés et matériaux utiles pour appliquer des agents pharmacologiques sur l'oreille. Ces procédés comportent la délivrance d'une composition, contenant au moins un agent de viscosité et au moins un agent pharmacologique, sur la surface de l'épiderme de la membrane du tympan par le conduit auditif externe de l'oreille. Cette composition est cédée à la membrane du tympan sous forme fluide et, une fois appliquée sur la membrane du tympan, elle devient suffisamment visqueuse pour que l'agent pharmacologique se localise sur la membrane du tympan. On peut utiliser de telles compositions pour un traitement prophylactique et/ou thérapeutique des états pathologiques de l'oreille moyenne et de l'oreille interne, y compris l'otite moyenne.
Cheung Belinda W. Y.
Sawchuk Ronald J.
Regents Of The University Of Minnesota
Smart & Biggar
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