Chimeric adenoviral coat protein and methods of using same

Details Chimeric adenoviral coat protein and methods of using same Chimeric adenoviral coat protein and methods of using same

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) C07K 14/075 (2006.01) C12N 5/10 (2006.01) C12N 15/34 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2283628

The present invention provides a chimeric adenoviral coat protein (particularly a chimeric adenovirus hexon protein). The chimeric adenovirus coat protein has a decreased ability or inability to be recognized by a neutralizing antibody directed against the corresponding wild-type adenovirus coat protein.

La présente invention concerne une protéine de manteau d'adénovirus chimère (en particulier une protéine hexon d'adénovirus chimère). La protéine de manteau d'adénovirus chimère présente une capacité réduite ou une incapacité à être reconnue par un anticorps neutralisant agissant contre la protéine de manteau d'adénovirus de type sauvage correspondante.

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