Nucleic acid ligands to cd40ligand

Details Nucleic acid ligands to cd40ligand Nucleic acid ligands to cd40ligand

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2380545

Methods are provided for generating nucleic acid ligands of CD40ligand. The methods of the invention use the SELEX method for the isolation of nucleic acid ligands. The invention also includes nucleic acid ligands to CD40ligand, and methods and compositions for the treatment and diagnosis of disease using the nucleic acid ligands.

L'invention concerne des procédés permettant de produire des ligands acide nucléique réactifs vis-à-vis de ligand CD40. Ces procédés utilisent le procédé SELEX pour l'isolation de ligands acide nucléique. L'invention concerne également des ligands acide nucléique réactifs vis-à-vis de ligand CD40, ainsi que des procédés et des compositions destinées au traitement et au diagnostic de maladies au moyen de ces ligands acide nucléique.

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