Optically active triazole derivative, process for producing...

C - Chemistry – Metallurgy – 07 – D

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C07D 249/08 (2006.01) A61K 31/41 (2006.01) A61K 31/695 (2006.01) C07D 521/00 (2006.01) C07F 7/08 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2180091

An optically active triazole derivative represented by the following formula (I) is disclosed: Image (I) wherein R1 and R each represents a hydrogen atom, a halogen atom or a C1-C6 haloalkyl group; R3 represents a phenyl group, a phenyl group substituted with a halogen atom, a C1-C6 haloalkyl group, a C1-C6 haloalkoxy group or a cyano group, or a silyl group substituted with a C1-C6 alkyl group, a phenyl group or a halogen-substituted phenyl group; and n is an integer of 1 or 2, provided that R1 and R are not hydrogen atoms at the same time, or a pharmaceutically acceptable salt thereof. A method for producing it, an antifungal agent comprising it, and a method for treating mycosis by using it are also disclosed.

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