Substituted azoles

Details Substituted azoles Substituted azoles

C - Chemistry, Metallurgy

07

D

C07D 413/00 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/04 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2370417

Compounds of formula (I) wherein the symbols have meaning as defined herein, are p38 MAP kinase inhibitors, and are useful pharmaceutically for treating TNF.alpha. and IL-1 mediated diseases, such as rheumatoid arthritis, and diseases of bone metabolism, e.g. osteoporosis.

L'invention concerne des composés correspondant à la formule (I) dans laquelle les symboles possèdent les notations données dans la description. Ces composés constituent des inhibiteurs de la protéine kinase p38 activée par les mitogènes et sont utiles dans le domaine pharmaceutique pour traiter les maladies induites par le facteur de nécrose tumorale .alpha. et IL-1, telles que la polyarthrite rhumatoïde, ainsi que des maladies du métabolisme osseux, par exemple l'ostéoporose.

Affiliated with

Also associated with

Rating

Substituted azoles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted azoles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted azoles will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1907826