Methods for treating bleeding disorders using sulfated...

Details Methods for treating bleeding disorders using sulfated... Methods for treating bleeding disorders using sulfated...

A - Human Necessities

61

K

A61K 31/727 (2006.01) A61K 31/717 (2006.01)

Patent

CA 2567495

Methods for treating bleeding disorders using non-anticoagulant sulfated polysaccharides (NASPs) as procoagulants are disclosed. NASPs can be administered as single agents, or in combination with one another, or with other medications (such as factors VII, VIII and IX) to promote hemostasis. In particular, the use of NASPs in treatment of bleeding disorders, including congenital coagulation disorders, acquired coagulation disorders, and trauma induced hemorrhagic conditions is described.

L'invention concerne des procédés de traitement des troubles de saignement qui font intervenir des polysaccharides sulfatés non anticoagulants (NASP) comme procoagulants. Les NASP peuvent être administrés comme agents uniques, ou en combinaison avec un ou plusieurs autres médicaments (tels que les facteurs VII, VIII et IX) pour favoriser l'hémostase. Plus particulièrement, l'invention concerne l'utilisation des NASP dans le traitement des troubles de saignement, y compris les troubles de coagulation congénitaux, les troubles de coagulation acquis, ainsi que les états hémorragiques d'origine traumatique.

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