Method for diagnosing pancreatic cancer

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2500482

Objective methods for detecting and diagnosing pancreatic cancer (PNC) are described herein. In one embodiment, the diagnostic method involves determining the expression level of PNC-associated gene that discriminates between PNC cells and normal cells. The present invention further provides methods of screening for therapeutic agents useful in the treatment of pancreatic cancer, methods of treating pancreatic cancer and method of vaccinating a subject against pancreatic cancer.

L'invention concerne des méthodes de détection et de diagnostic du cancer du pancréas (PNC). Dans un mode de réalisation, la méthode de diagnostic consiste à déterminer le niveau d'expression d'un gène associé au PNC qui différencie les cellules du PNC des cellules normales. L'invention concerne également des méthodes de criblage d'agents thérapeutiques utiles dans le traitement du cancer du pancréas, des méthodes de traitement de ce cancer et une méthode de vaccination d'un sujet contre le cancer du pancréas.

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