Dispersion with nonionic emulsifier

C - Chemistry – Metallurgy – 08 – L

Patent

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Details

C08L 33/12 (2006.01) A61K 9/20 (2006.01) A61K 9/32 (2006.01) A61K 9/50 (2006.01) B01F 17/00 (2006.01) C08F 2/30 (2006.01) C08F 220/18 (2006.01) C08L 33/06 (2006.01)

Patent

CA 2386932

The invention relates to a dispersion that is suitable for the use as a coating and binding means for forms of medicaments. The inventive dispersion has a solids content of 10 to 70 wt. % and consists of a) 90 to 99 wt. % of a methacrylate copolymer which consists of at least up to 90 wt. % of (meth)acrylate monomers and detects a glass temperature Tg of 20 ~C to +20 ~C according to the DSC method, whereby said monomers have neutral radicals. Said dispersion also consists of 1-10 wt. % of a non-ionic emulsifier having an HLB value of 15.2 to 17.3.

L'invention concerne une dispersion pouvant être utilisée comme agent de revêtement et liant pour des formes médicamenteuses, dont la teneur en solides, qui est de 10 à 70 % en poids, se compose de: a) 90 à 99 % en poids d'un copolymère de méthacrylate, qui est constitué lui-même d'une proportion minimale de monomères de (méth)acrylate comportant des restes neutres de 90 % en poids, et présente une température de transition vitreuse tv de - 20 ·C à + 20 ·C, définie selon le procédé DSC; et b) 1-10 % en poids d'un émulsifiant non ionique présentant un rapport hydrophile-lipophile de 15,2 à 17,3.

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