Transcription factor aprf

Details Transcription factor aprf Transcription factor aprf

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2145969

Mammal transcription factor APRF, process for the preparation of it, DNAs encoding the said product, replication and expression vector comprising the said DNA, host cells transformed or transfected with the said replication and expression vector, evaluating and screening method for searching an inhibitory agent on the function of APRF and an inhibitory agent against the function of the said APRF. The peptide of the resent invention (APRF) may be useful for complement or suppression of the function of APRF, screening an inhibitory agent against the function of APRF. Inhibiting agent containing the said product as active ingredient of the present invention may be also useful for treatment of diseases related cytokine such as IL-6 i.e. inflammatory diseases.

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