Modifying the expression of the fsh beta gene by homologous...

Details Modifying the expression of the fsh beta gene by homologous... Modifying the expression of the fsh beta gene by homologous...

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) A61K 48/00 (2006.01) C07K 14/59 (2006.01) C12N 5/10 (2006.01) C12N 15/67 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2328506

An isolated nucleic acid molecule that hybridizes under stringent conditions, or shares at least 80 % sequence identity, with a defined genomic region upstream of the coding region of a FSH.beta. gene, and a DNA construct containing that nucleic acid molecule as a targeting sequence for homologous recombination.

On décrit une molécule d'acide nucléique qui s'hybride dans des conditions rigoureuses ou partage au moins 80 % d'une identité de séquence avec une région génomique définie située en amont de la région de codage du gène FSH.beta.. On décrit également une construction d'ADN contenant cette molécule d'acide nucléique en tant que séquence de ciblage pour une recombinaison homologue.

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