Neovascularization inhibitor containing tissue factor...

A - Human Necessities – 61 – K

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A61K 38/57 (2006.01)

Patent

CA 2250008

An inhibitor for neovascularization caused by the proliferation of vascular endothelial cells characterized by containing a tissue factor pathway inhibitor (TFPI) as the active ingredient. The TFPI-containing inhibitor can effectively inhibit the neovascularization, so that it is useful as a preventive or remedy for pathological conditions accompanying neovascularization, such as malignant tumor.

L'invention concerne un inhibiteur de la néoformation de vaisseaux sanguins due à la prolifération des cellules endothéliales vasculaires, et qui se caractérise en qu'il renferme un inhibiteur du mécanisme d'action du facteur tissulaire (TPFI) jouant le rôle d'ingrédient actif. Cet inhibiteur renfermant TPFI peut inhiber efficacement la néoformation de vaisseaux sanguins et peut être, par conséquent, utile comme agent prophylactique ou comme remède à des états pathologiques liés à la néoformation de vaisseaux sanguins telle que des tumeurs malignes.

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