Stable gel formulation for topical treatment of skin conditions

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/455 (2006.01) A61K 8/67 (2006.01) A61K 9/10 (2006.01) A61K 31/4436 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2191773

The present invention provides a stable gel formulation for topical treatment of skin conditions in humans. The stable gel formulation includes an active agent, having activity for treatment of acne and psoriasis, which is insoluble in water and a plurality of nonaqueous vehicles for both sotubilizing said active agent and forming a gel therewith enabling topical application of the gel to a skin condition. The plurality of vehicles am each present in amounts, and in combination, m control release of the active agent from the gel to the skin condition.

Une composition de gel stable pour le traitement topique de maladies de la peau chez les humains comprend un principe actif de traitement de l'acné et du psoriasis, insoluble dans l'eau, et une pluralité d'excipients non aqueux pour solubiliser et gélifier le principe actif, ce qui permet d'appliquer localement le gel sur la peau malade. La quantité et l'association des divers excipients sont sélectionnées pour régler la libération sur la peau malade du principe actif contenu dans le gel.

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