Muramyl peptide derivatives and immunoregulating...

C - Chemistry – Metallurgy – 07 – K

Patent

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530/9, 167/103.8

C07K 9/00 (2006.01) A61K 38/14 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2011275

ABSTRACT OF THE DISCLOSURE Muramyl peptide derivatives of the formula : Image (I) wherein "Ala" is Image ; "isoGln" is Image ; R1 is R3O- or R3S-[R3 is Image (k is an integer from 8 to 12; q is an integer from 10 to 22) or R3 is Image (m is an integer from 11 to 17; n is an integer from 11 to 17)]; and R2 is hydrogen atom or -CO-(CH2)p-CH3 (p is an integer from 8 to 22); which act on in vivo immunomechanism of human beings and livestock (in particular cells relevant immue responses) and are useful as immunoregulating agents.

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