Selective hydroxamate based mmp inhibitors

Details Selective hydroxamate based mmp inhibitors Selective hydroxamate based mmp inhibitors

C - Chemistry, Metallurgy

07

C

C07C 311/19 (2006.01) A61K 31/18 (2006.01) A61P 9/00 (2006.01) C07C 311/29 (2006.01) C07C 311/42 (2006.01) C07C 311/46 (2006.01) C07C 311/47 (2006.01) C07D 213/42 (2006.01) C07D 295/12 (2006.01)

Patent

CA 2644783

The present invention provides a compound of formula (I): said compound is inhibitor of MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-9, and/or MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-9, and/or MMP-12 and/or MMP-13. Finally, the present invention also provides a pharmaceutical composition.

La présente invention concerne un composé de formule (I) : Ledit composé est un inhibiteur de la MMP-9 et/ou de la MMP-12 et/ou de la MMP-13, et il peut ainsi être utilisé pour le traitement d'une maladie ou d'une affection caractérisée par une activité anormale de la MMP-9 et/ou de la MMP-12 et/ou de la MMP-13. En conséquence, le composé de formule (I) peut être utilisé pour le traitement d'une maladie ou d'une affection induite par la MMP-9 et/ou par la MMP-12 et/ou par la MMP-13. Finalement, la présente invention concerne également une composition pharmaceutique.

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