Dual action dentifrice compositions to prevent...

A - Human Necessities – 61 – K

Patent

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A61K 8/19 (2006.01)

Patent

CA 2756993

The invention encompasses combinations of bioactive glass composition and potassium salts that are useful in con-junction with delivery agent such as, for ex-ample, toothpastes, mouthwashes, and oral gels. In certain embodiments, the composi-tions of the invention form a rapid and con-tinuous reaction with body fluids (e.g., sali-va) to promote the immediate and long- term release of Ca and P ions to produce a stable crystalline layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.

La présente invention concerne des combinaisons associant une composition à base de verre bioactif et des sels de potassium, qui se révèlent utilisables en association avec un support d'administration tel que, par exemple, les pâtes dentifrices, les bains de bouche et les gels buccaux. Dans certains modes de réalisation, les compositions de l'invention réagissent rapidement et en continu avec les liquides organiques (par exemple la salive) pour favoriser la libération immédiate et à long terme d'ions Ca et P en vue de la production d'une couche cristalline stable se déposant sur et dans les tubules dentinaires en vue de la réduction immédiate et à long terme de l'hypersensibilité de la dentine, ainsi que de la reminéralisation de la surface dentaire.

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