Novel indolocarbazole derivatives useful for the treatment...

Details Novel indolocarbazole derivatives useful for the treatment... Novel indolocarbazole derivatives useful for the treatment...

C - Chemistry, Metallurgy

07

D

C07D 487/22 (2006.01) A61K 31/551 (2006.01) A61P 25/28 (2006.01) C07D 487/14 (2006.01)

Patent

CA 2336419

Novel indolocarbazole derivatives potentially useful for the treatment of dementias characterized by tau hyperphosphorylation [Alzheimer's disease (AD), frontal lobe degeneration (FLD), argyrophilic grains disease, subacute sclerotising panencephalitis (SSPE) as a late complication of viral infection in the CNS], and cancer.

La présente invention concerne des dérivés d'indolocarbazole potentiellement utiles pour le traitement de démences caractérisées par une hyperphosphorylation de la protéine tau (maladie d'Alzheimer, dégénérescence du lobe frontal, argyrophilie granulaire, panencéphalite sclérosante subaiguë comme complication tardive d'infections virales dans le système nerveux central), et du cancer.

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