Human b-cell translocation genes-2 and 3

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2266425

The present invention relates to novel antiproliferative genes. More specifically, isolated nucleic acid molecules are provided encoding the human B-cell translocation genes 2 and 3 (BTG-2 and BTG-3). BTG-2 and BTG-3 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same.

La présente invention concerne de nouveaux gènes antiproliférateurs, plus particulièrement des molécules d'acide nucléique isolées codant les gènes 2 et 3 de translocation des lymphocytes B humains (BTG-2 et BTG-3). Elle concerne également des polypeptides de BTG-2 et de BTG-3, ainsi que des vecteurs, des cellules hôtes et des méthodes de recombinaison permettant de produire lesdits gènes.

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