C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/66 (2006.01) C12P 15/00 (2006.01) C12P 21/06 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2395676
The present invention relates to novel proteins. More specifically, isolated nucleic acid molecules are provided encoding novel polypeptides. Novel polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells,and recombinant and synthetic methods for producing human polynucleotides and/or polypeptides, and antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to these novel polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
L'invention concerne de protéines, plus précisément, des molécules isolées d'acide nucléique codant de nouveaux polypeptides. Elle concerne de nouveaux polypeptides et des anticorps qui lient ces polypeptides, ainsi que des vecteurs, des cellules hôtes, et des procédés de recombinaison et de synthèse destinés à produire des polynucléotides humains et/ou des polypeptides et des anticorps. L'invention concerne également des procédés de diagnostic et thérapeutiques servant à diagnostiquer, à traiter, à prévenir et/ou à pronostiquer des troubles relatifs à ces nouveaux polypeptides. Elle concerne en outre des procédés de criblage destinés à identifier des agonistes et antagonistes desdits polynucléotides et polypeptides. Elle concerne enfin des procédés et/ou des compositions conçus pour inhiber ou renforcer la production et la fonction desdits polypeptides.
Barash Steven C.
Rosen Craig A.
Ruben Steven M.
Barash Steven C.
Human Genome Sciences Inc.
Mbm & Co.
Rosen Craig A.
Ruben Steven M.
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