Reversible inhibitors of monoamine oxidase a and b

Details Reversible inhibitors of monoamine oxidase a and b Reversible inhibitors of monoamine oxidase a and b

C - Chemistry, Metallurgy

07

C

C07C 255/46 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/277 (2006.01) C07C 235/34 (2006.01) C07C 237/24 (2006.01) C07D 213/56 (2006.01)

Patent

CA 2610659

The instant invention relates to compounds of formula I, diagrammed below, wherein R3, E, D and Y are defined in the application, which are useful as reversible inhibitors of monoamine oxidase-B and/or monoamine oxidase-A, and therefore useful to treat or prevent neurological diseases or conditions in mammals, preferably humans.

La présente invention concerne des composés de formule I, représentés dans les diagrammes ci-dessous, où R3, E, D et Y sont définis dans la demande, utilisés comme inhibiteurs réversibles de la monoamine oxydase B et/ou de la monoamine oxydase A, et par conséquent utiles pour traiter ou prévenir des maladies ou des conditions neurologiques chez des mammifères, de préférence chez des êtres humains.

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