A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/711 (2006.01) A61K 31/7105 (2006.01) A61K 39/39 (2006.01) A61P 31/12 (2006.01) C07H 21/00 (2006.01)
Patent
CA 2402312
The invention provides new methods of preventing and/or treating herpes virus infections, particularly reducing infection, one or more symptoms and recurrence of one or more symptoms of herpes simplex virus infection. A polynucleotide comprising an immunostimulatory sequence (an "ISS") is administered to an individual which is at risk of being exposed to alphaherpesvirinae, has been exposed to alphaherpesvirinae or is infected with alphaherpesvirinae. The ISS is administered without any alphaherpesvirinae antigens. Administration of the ISS results in reduced incidence, recurrence, and severity of one or more symptoms of alphaherpesvirinae infection.
L'invention concerne de nouvelles méthodes de prévention et/ou de traitement d'infections à herpèsvirus, notamment de réduction de l'infection, d'un ou de plusieurs symptômes, ou de récurrence d'un ou de plusieurs symptômes d'infection à herpèsvirus de type 1. Un polynucléotide comprenant une séquence immunostimulatrice ("ISS") est administré à un individu susceptible d'être exposé àalphaherpesvirinae, exposé à alphaherpesvirinae, ou infecté par alphaherpesvirinae. La ISS est administrée sans aucun antigène anti-alphaherpesvirinae. L'administration de la ISS diminue l'incidence, la récurrence ou la gravité d'un ou de plusieurs symtômes d'une infection à alphaherpesvirinae.
Borden Ladner Gervais Llp
Dynavax Technologies Corporation
LandOfFree
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