Aminopyrazine derivatives and medicines

Details Aminopyrazine derivatives and medicines Aminopyrazine derivatives and medicines

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/497 (2006.01) A61K 31/506 (2006.01) A61P 7/00 (2006.01) A61P 35/02 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2751695

A compound represented by general formula [1] satisfying the following (I) or (II), or a pharmaceutical acceptable salt of the compound. (see formula 1) (I) X is CH or N; R1 is a halogen atom,; and R2 is H, a halogen atom, CN, [2], [3], [8], [9], an -O-alkyl, an -O-(saturated ring), etc. [2]: -C(R C)(R D)(R E) {R C to R E each are H, an alkyl, etc.} [3]: -N(R F)(R G) {R F and R G each are H, OH, amino, a (hetero)aryl, etc.} [8]: -C(=O)R L {R L is an alkyl, OH, an alkoxy, amino, etc.} [9]: a (substituted)phenyl; (II) X is >C-C(=O)R B {R B is a(substituted)amino, an alkoxy, OH, etc.}; R1 is a halogen atom; R2 is H; R3 is H or OH; and R3 and R4 each are H or an alkyl.

L'invention porte sur un composé représenté par la formule générale [1] satisfaisant les formules suivantes (I) ou (II), ou sur un sel de qualité pharmaceutique du composé. (I) X représente CH ou N ; R1 représente un atome d'halogène, et R2 représente H, un atome d'halogène, CN, [2], [3], [8], [9], un O-alkyle, un O-(cycle saturé), etc. [2] : -C(RC)(RD)(RE) {RC à RE représentent chacun H, un alkyle, etc. [3] : -N(RF)(RG) {RF et RG représentent chacun H, OH, amino, un (hétéro)aryle, etc. [8] : -C(=O)RL {RL représente un alkyle, OH, un alcoxy, amino, etc. [9] : un phényle (substitué) (II) X représente > C-C(=O)RB {RB représente un amino (substitué), un alcoxy, OH, etc. ; R1 représente un atome d'halogène ; R2 représente H ; R3 représente H ou OH ; et R4 et R5 représentent chacun H ou un alkyle.

Affiliated with

Also associated with

Rating

Aminopyrazine derivatives and medicines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aminopyrazine derivatives and medicines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aminopyrazine derivatives and medicines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1913401