A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/519 (2006.01) A61K 31/375 (2006.01) A61K 31/616 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2556489
This invention relates to the use of folates for the prevention and/or treatment of cardiovascular diseases, such as atheroscle-rosis, and in particular for modulating endothelial nitric oxide synthase (eNOS). The invention further relates to pharmaceutical preparations consisting of said folates and a pharmaceutically acceptable carrier, optionally in combination with other pharma-ceutically active agents, as well as therapeutic methods using said folates or pharmaceutical preparations thereof.
La présente invention porte sur l'utilisation de folates pour prévenir et/ou traiter des maladies cardiovasculaires, comme l'athérosclérose, et, en particulier, pour réguler l'oxyde nitrique synthétase endothéliale. L'invention concerne également des préparations pharmaceutiques composées desdits folates et un vecteur pharmaceutiquement acceptable, facultativement en combinaison avec d'autres agents pharmaceutiquement actifs, de même que des méthodes therapeutiques faisant appel à ces folates ou à des préparations pharmaceutiques de ceux-ci.
Antoniades Charalambos
Channon Keith M.
Moser Rudolf
Shirodaria Cheerag
Merck & Cie
Merck Eprova Ag
Riches Mckenzie & Herbert Llp
LandOfFree
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