Recombinant foamy virus vectors for medicinal and diagnostic...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/867 (2006.01) A61K 35/76 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2124769

The present invention relates to the preparation of novel vector systems which are generated by in-vitro recombina-tion, using gene technology, of nucleic acids from foamy virus species and of exogenous nucleic acid, and are produced by suitable host cells or by recombinantly altered packaging cell lines. The recombinant preparation of particularly suitable packaging cell lines is likewise a constituent of this invention. The invention is distin-guished by the safe and efficient transfer by foamy virus vectors of therapeutic and other genes into eukaryotic cells.

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