A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/473 (2006.01) A61K 31/365 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2741490
The present invention relates to therapeutic compounds that are Nrf2-ARE pathway activators suitable for the treatment of diseases known to be mediated by oxidative stress such as motor neurone disease. The invention also includes com-pounds identified by the methods of the invention for treatment of neurodegenerative diseases.
La présente invention concerne des composés thérapeutiques qui sont des activateurs de la voie Nrf2-ARE, adaptés pour le traitement de maladies connues comme étant véhiculées par un stress oxydatif telles que la sclérose latérale amyotrophique. Linvention comprend en outre des composés identifiés par les procédés de linvention pour le traitement de maladies neurodégénératives.
Barber Sian
Higginbottom Adrian
Mead Richard
Shaw Pamela
Ridout & Maybee Llp
University Of Sheffield
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