C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/50 (2006.01) A61K 31/4709 (2006.01) C07D 221/12 (2006.01) C07D 409/04 (2006.01)
Patent
CA 2681757
The present teachings relate to novel compounds of formula I: wherein the constituent variables are as defined herein. Compounds of the present teachings can act as antagonists of the mammalian adhesion proteins known as selectins. Methods for treating or preventing selectin-mediated disorders are provided, which include administration of these compounds in a therapeutically effective amount.
La présente invention concerne de nouveaux composés de la formule I: LA FORMULE CHIMIQUE DOIT ETRE INSEREE ICI TELLE QU'ELLE APPARAiT SUR LE RESUME DU FORMAT PAPIER, où les variables sont telles que définies ici. Les composés de la présente invention peuvent agir comme antagonistes des protéines mammaliennes d'adhésion connus comme sélectines. Des procédés de traitement ou de prévention de désordres à médiation par les sélectines sont décrits, lesquels comprennent l'administration de ces composés en une quantité thérapeutiquement efficace.
Bedard Patricia Ward
Huang Adrian
Janz Kristin Marie
Kaila Neelu
Moretto Alessandro Fabio
Smart & Biggar
Wyeth
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