Structured triglycerides and emulsions comprising same

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 53/00 (2006.01) A61K 31/225 (2006.01) A61K 31/23 (2006.01)

Patent

CA 2557927

The present invention relates to structured triglyceride, to parental nutrition emulsions comprising same, and use thereof. In particular, the invention relates to structured triglycerides comprising at least one medium chain C6-C12 fatty acid and at least one fatty acid selected from the group consisting of long chain C14-C18 or very long chain C20-C22 fatty acids, preferably each fatty acid is present in a predetermined position of the glycerol backbone. The parenteral nutrition emulsions are particularly useful for nourishing preterm-and term-infants, children, critically ill patients, and cancer patients.

L'invention concerne des triglycérides structurés, des émulsions de nutrition parentérale contenant ces triglycérides, et les utilisations de celles-ci. L'invention concerne plus particulièrement des triglycérides structurés contenant au moins un acide gras C6-C12 à chaîne moyenne, et au moins un acide gras choisi dans le groupe constitué par les acides gras C14-C18 à longue chaîne et les acides gras C20-C22 à très longue chaîne, chaque acide gras étant de préférence présent dans une position prédéterminée de la chaîne principale de glycérol. Les émulsions de nutrition parentérale sont particulièrement indiquées pour la nutrition des nouveau-nés prématurés ou à terme, des enfants, des patients en phase critique, et des patients souffrant d'un cancer.

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