Use of specific dose of fondaparinux sodium for the...

A - Human Necessities – 61 – K

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A61K 31/7024 (2006.01) A61K 31/702 (2006.01) A61K 31/715 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2465776

The invention relates to the use of a dose of 2.5 mg of the pentasaccharide methyl O-(2-deoxy-2-sulfoamino-6-O-sulfo-.alpha.-D-glucopyranosyl)-(1-4)-O- (.beta.-D-glucopyranosyl uronic acid)-(1-4)-O-(2-deoxy-2-sulfoamino-3,6-di-O- sulfo-.alpha.-D-glucopyranosyl)-(1-4)-O-(2-O-sulfo-.alpha.-L-idopyranosyl uronic acid)-(1-4)-2-deoxy-2-sulfoamino-6-O-sulfo-.alpha.-D-glucopyranoside or a pharmaceutically acceptable salt thereof for the preparation of a medicament for the treatment of Acute Coronary Syndromes (ACS).

La présente invention concerne l'utilisation d'une dose de 2,5 mg de O-(2-deoxy-2-sulfoamino-6-O-sulfo-.alpha.-D-glucopyranosyl)-(1.fwdarw.4)-O-(acide .beta.-D-glucopyranosyl uronique)-(1.fwdarw.4)-O-(2-deoxy-2-sulfoamino-3,6-di-O-sulfo-.alpha.-D-glucopyranosyl)-(1.fwdarw.4)-O-(acide 2-O-sulfo-.alpha.-L-idopyranosyl uronique)-(1.fwdarw.4)-2-deoxy-2-sulfoamino-6-O-sulfo-.alpha.-D-glucopyranoside ou d'un sel de celui-ci, acceptable d'un point de vue pharmaceutique, pour préparer un médicament servant à traiter des syndromes coronariens aigus (Acute Coronary Syndromes : ACS).

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