Duloxetine hydrochloride delayed release formulations

Details Duloxetine hydrochloride delayed release formulations Duloxetine hydrochloride delayed release formulations

A - Human Necessities

61

K

A61K 31/381 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2651716

Delayed release formulations of duloxetine hydrochloride and methods for its manufacture are described. A preferred formulation includes an inert core, a drug layer comprising duloxetine hydrochloride, a separating layer and an enteric layer comprising at least one of methacrylic acid copolymer and hydroxypropyl methyl cellulose phthalate.

L'invention concerne des formulations à libération retardée de chlorhydrate de duloxétine et leurs procédés d'élaboration. Une formulation préférée comprend un noyau inerte, une couche de médicament contenant du chlorhydrate de duloxétine, une couche de séparation et une couche entérique contenant un copolymère d'acide méthacrylique et/ou un phtalate d'hydroxypropyl méthylcellulose.

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