Parapoxvirus vectors

Details Parapoxvirus vectors Parapoxvirus vectors

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/435 (2006.01) C12N 15/863 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2250041

The invention is directed to parapoxvirus vectors. Specifically provided are orf virus vectors containing exogenous DNA. The exogenous DNA may encode a heterologous peptide or polypeptide of which expression is desired, or may encode an antigen capable of inducing an immune response. The capacity to express antigens make these vectors suitable for use in vaccines.

Cette invention se rapporte à des vecteurs de parapoxvirus. Elle concerne spécifiquement des vecteurs de virus d'orf contenant de l'ADN exogène. Ledit ADN exogène peut coder un peptide ou un polypeptide hétérologue dont l'expression est souhaitée, ou il peut coder un antigène susceptible d'induire une réponse immunitaire. La capacité de ces vecteurs à exprimer des antigènes fait qu'ils conviennent à la fabrication de vaccins.

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