Promoter and regulator sequences ha ds10 g1: a gene lea of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/82 (2006.01) A01H 5/00 (2006.01) C07K 14/415 (2006.01) C12N 15/29 (2006.01)

Patent

CA 2319209

The present invention discloses the isolation and characterization in transgenic tobacco plants of the promoter and regulator sequences of a gene LEA-I of sunflower, Ha ds10 G1. These sequences present characteristics which are extremely appropriate to be used in the modification of seeds (for example of reserve substances). The advantages of their possible use in transgenic plants are demonstrated through examples such as studies related to the accumulation and location of RNAm Ha ds10 in the homologous system. Said studies show both the high expression levels reached during embryogenesis from the early maturation phases and the absolute specificity of the seed, together with a homogenous location in embryos which is finally restricted essentially to the soft tissue in palisade of the cotyledons, a tissue specialized in the accumulation of reserve substances in the sunflower.

L'invention consiste à isoler et caractériser chez le plantes transgéniques de tabac le promoteur et les séquences régulatrices d'un gène LEA-I de tournesol, Ha ds10 G1. Ces séquences présentent des caractéristiques se prêtant parfaitement à leur utilisation dans la modification de graines (p. ex. de substances de restes). Les avantages, découlant de son utilisation sur les plantes transgéniques, ont été démontrés par le biais d'exemples, tels que des études sur l'accumulation et la localisation de l'ARNm Ha ds10 dans le système homologue. Ces études mettent en avant les niveaux élevés d'expression du gène atteints au cours de l'embryogenèse depuis les phases précoces de la maturation et sa spécificité absolue par rapport à la graine, ainsi que sa localisation homogène de l'ARNm chez les embryons qui se limite essentiellement au parenchyme en palissade des cotylédons, tissus spécialisés dans l'accumulation de substances de réserves dans le tournesol.

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