Lipid vehicle drug delivery composition containing vitamin e

Details Lipid vehicle drug delivery composition containing vitamin e Lipid vehicle drug delivery composition containing vitamin e

A - Human Necessities

61

K

A61K 47/22 (2006.01) A61K 9/107 (2006.01) A61K 9/127 (2006.01)

Patent

CA 2224734

The present invention provides a drug delivery composition comprising a lipid vehicle containing a drug and Vitamin E to enhance the solubility of the active drug in the lipid vehicle. The composition is particularly useful for drugs which are poorly soluble. The composition may be in the form of a liposome or an oil-in-water emulsion. The Vitamin E may be mixed with a pharmaceutically acceptable oil such as a marine oil or a vegetable oil.

La présente invention concerne une composition, pour l'administration de médicaments, comprenant un véhicule lipidique qui contient un médicament et de la vitamine E pour augmenter la solubilité du principe actif dans le véhicule lipidique. Cette composition est particulièrement utile pour les médicaments dont la solubilité est faible. Elle peut se présenter sous la forme d'un liposome ou d'une émulsion d'huile dans l'eau. La vitamine E peut être mélangée avec une huile acceptable en pharmacie, comme l'huile marine ou une huile végétale. .

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