Potent compstatin analogs

Details Potent compstatin analogs Potent compstatin analogs

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/08 (2006.01) A61K 38/16 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2631443

Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds.

La présente invention concerne des composés comprenant des peptides et des peptidomimétiques capables de se lier à la protéine C3 et d'inhiber l'activation du complément. Ces composés présentent une activité d'activation du complément bien supérieure à celle des composés actuellement disponibles.

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