Solid bodies containing active substances and a structure...

Details Solid bodies containing active substances and a structure... Solid bodies containing active substances and a structure...

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 8/04 (2006.01) A61K 8/64 (2006.01) A61K 8/65 (2006.01) A61K 8/97 (2006.01) A61K 9/16 (2006.01) A61K 31/44 (2006.01) A61K 47/42 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2128244

The invention relates to accurately meterable shaped articles, for example granules or pellets, containing hydrophilic macromolecules, active compounds and optionally further pharmaceutically acceptable structure-forming substances and auxiliaries, the active compound being present in a matrix in dissolved, suspended or emulsified form, and a novel process for the production of these shaped articles, the process being particularly economically and ecologically acceptable, and use of the shaped articles as medicaments, in which the bioavailability, shelf life and tolerability is increased. Using the shaped articles or mixtures according to the invention, intermediates or final products for pharmacy, cosmetics, diagnosis, analysis or dietetics (healthcare) can additionally be advantageously prepared.

L'invention a trait à des articles formés précisément mesurables, par exemple, des granules ou des pastilles, contenant des macromolécules hydrophiles, des composés actifs et, possiblement, d'autres substances et auxiliaires formant des structures pharmaceutiquement acceptables, le principe actif étant présent dans un support sous forme dissoute ou émulsifiée ou en suspension, et un nouveau procédé pour la production de ces articles formés, procédé qui est particulièrement avantageux du point de vue économique et écologique, et l'usage des articles formés comme médicaments dont la biodisponibilité, la durée de conservation et la tolérabilité sont améliorées. L'usage des articles formés ou des mélanges, selon l'invention, des intermédiaires et des produits finis dans des produits pharmaceutiques, des cosmétiques ou pour le diagnostic, l'analyse ou la diététique (soins de santé) peut également se révéler avantageux.

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