An apparatus and method for performing selective...

A - Human Necessities – 61 – B

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A61B 18/18 (2006.01) A61F 9/008 (2006.01) A61B 18/00 (2006.01) A61B 18/20 (2006.01)

Patent

CA 2410962

Selective photocoagulation of particular cells, tissue or portion of tissue can be aided by monitoring microcavitation within the material exposed to electromagnetic radiation (12). The information gained by the detection of microcavitation events can be used to modulate the intensity of the radiation (12) to prevent significant thermal energy transmission and mechanical damage to cells, tissues or portions of tissues which are not directly exposed, but prone to thermal damage by such energy transmission. Detection of microcavitation also serves as a valuable therapeutic endpoint. The methods of the invention are applicable to laser eye surgery, since the target cells of several therapeutic photocoagulation methods, the retinal pigment epithelial (RPE) cells are proximate to photoreceptor cells. The inventive methods can help prevent the formation of blind spots that can be associated with laser eye surgery. Other fields of laser surgery can also be readily adapted to the methods described herein.

Cette invention concerne un procédé permettant de seconder la photocoagulation de cellules, de tissus ou de portions de tissus particuliers par la détection de la microcavitation dans la matière exposée au rayonnement (12) électromagnétique. L'information obtenue par la détection des événement de microcavitation peut servir à moduler l'intensité du rayonnement (12) afin d'empêcher une transmission d'énergie thermique élevée et l'apparition de dégâts dans les cellules, tissus ou portions de tissus qui ne sont pas exposés directement mais risquent d'être endommagés par la chaleur lors d'une telle transmission d'énergie. La détection de la microcavitation constitue également un précieux critère thérapeutique. Ces procédés peuvent être appliqués à la chirurgie de l'oeil étant donné que les cellules cibles d'un grand nombre de procédés de photocoagulation thérapeutique, les cellules de l'épithélium pigmentaire rétinien, sont adjacentes aux cellules photoréceptrices. Ces procédés contribuent à prévenir la formation de taches aveugles associées à la chirurgie au laser de l'oeil. D'autres domaines de la chirurgie au laser peuvent également être facilement adaptés aux procédés décrits.

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