A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/12 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/167 (2006.01) A61K 31/245 (2006.01) A61K 31/435 (2006.01) A61K 31/445 (2006.01)
Patent
CA 2156821
The composition of the present invention combines the local anaesthetic lidocaine in free base form and the non-CFC aerosol propellant HFC-134a (1,1,1,2-tetrafluoroethane; CF3CH2F or HFC-227 (1,1,1,2,3,3,3- Heptafluoropropane; CF3CHFCF3), or a combination thereof, thus incorporating previously-unattainable amounts of the lidocaine free base in solution in a non-CFC aerosol propellant. This particular form of relatively-concentrated cosolvent-free anaesthetic permits improved inhalation delivery to the airway and lung, and topical airway local anaesthesia is thus readily provided. A method in accordance with the invention provides for release of the anaesthetic in aerosolized form of selected dosage from a canister containing the pressurized local anaesthetic composition into a patient's respiratory system directly or by way of an airway.
Henry Richard A.
Perley-Robertson Hill & Mcdougall Llp
LandOfFree
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