Inhibitors of protein kinases

Details Inhibitors of protein kinases Inhibitors of protein kinases

C - Chemistry, Metallurgy

07

D

C07D 239/42 (2006.01) A61K 31/505 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2702008

Compounds of general Formula I, wherein R1, R2, R3, x, A and R a are as defined herein are inhibitors of cyclin-dependent kinases and are useful for preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases.

L'invention concerne les composés de formule générale I : où R1, R2, R3, x, A et Ra sont tels que définis ici, lesquels sont des inhibiteurs de kinases dépendantes de cycline et sont utiles pour prévenir et/ou traiter tout type de douleur, de troubles inflammatoires, de maladies immunologiques, de maladies prolifératives, de maladies infectieuses, de maladies cardio-vasculaires et de maladies neurodégénératives.

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