Glp-1 formulations

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/26 (2006.01) A61K 47/20 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01) A61K 47/28 (2006.01)

Patent

CA 2312190

Methods and formulations are presented that provide for a) the oral absorption of GLP-1 peptides that bind surfactants; and b) long-term storage of formulations containing these peptides. For example, a GLP-1/DSS complex is administered orally instead of parenterally, which is much more convenient for, and facilitates compliance with diabetic patients and persons with other GLP-1 treated conditions.

La présente invention concerne des procédés et des formulations permettant: a) l'absorption par voie orale des peptides GLP-1 fixant les surfactants; et b) la longue conservation des formulations renfermant ces peptides. Par exemple, un complexe GLP-1/DSS est administré par voie orale et non pas par voie parentérale, car ce mode d'administration convient mieux aux diabétiques et aux personnes souffrant d'autres troubles traités par les GLP-1, et il facilite la conformité de ce traitement avec un autre.

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