Synthetic aglucodalbaheptide antibiotics

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/06 (2006.01) A61K 38/08 (2006.01) C07K 9/00 (2006.01)

Patent

CA 2159728

Synthetic aglucodalbaheptides of formula (I) wherein W and Z, each independently, represent the relative portions of the aglycon of an antibiotic of the dalbaheptide group. Y represents a carboxylic group or a functional derivative of said carboxylic group; R and R1, each independently, represent hydrogen or a protecting group of the amino function. R2 represents hydrogen; and their salts with acid and bases as well as their inner salts. A process for producing the aglucodalbaheptide of formula (I) and their use as medicaments.

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