Secreted alpha-helical protein-31

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/19 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2374412

The present invention relates to polynucleotide and polypeptide molecules for mammalian secreted alpha helical protein-31 (zalpha31). The polypeptides, and polynucleotides encoding them, are a novel four-helix bundle cytokine and may be used to regulate the functioning of the immune system. The present invention also includes antibodies to the Zalpha31 polypeptides.

La présente invention porte sur des molécules polynucléotidiques et polypeptidiques de protéines 31 (zalpha 31) mammaliennes à hélice alpha sécrétées. Les polypeptides et les polynucléotides les codant sont une nouvelle cytokine en faisceau à quatre hélices et peuvent être utilisés pour réguler le fonctionnement du système immun. La présente invention porte également sur des anticorps contre les polypeptides Zalpha31.

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