Substituted pyridines as selective cyclooxygenase-2 inhibitors

Details Substituted pyridines as selective cyclooxygenase-2 inhibitors Substituted pyridines as selective cyclooxygenase-2 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/44 (2006.01) A61K 31/444 (2006.01) A61P 29/00 (2006.01) C07D 213/61 (2006.01) C07D 213/65 (2006.01) C07D 213/75 (2006.01) C07D 213/89 (2006.01)

Patent

CA 2412968

The invention encompasses the novel compound of formula (I) (see Formula I) as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of formula (I).

L'invention porte sur le nouveau composé ayant la formule (I) (voir la formule I), de même qu'une méthode permettant de traiter les maladies mettant en cause la COX-2. La méthode comprend l'administration d'une quantité thérapeutiquement efficace et non toxique du composés de formule I à un patient nécessitant ce traitement. L'invention porte aussi sur certaines compositions pharmaceutiques permettant de traiter des maladies faisant intervenir la COX-2, contenant des composés de la formule I.

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