C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/06 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) C07D 207/40 (2006.01) C07D 233/76 (2006.01) C07D 263/44 (2006.01) C07D 277/34 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2083891
T1126Y ABSTRACT HETEROCYCLIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY Compounds of formula (I): Image ( I ) wherein 1 Q1 represents a phenyl group substituted by one or more halo; naphthyl; indolyl; benzthiophenyl; benzofuranyl; benzyl; or fluorenyl; 1 R1 is H, C1-6alkyl or C2-6alkenyl; 1 R2 is phenyl(C1-4alkyl) optionally substituted in the phenyl ring by one or more groups selected from C1-6alkyl, C2-6alkenyl, C2-6alkynyl, halo, cyano, nitro, trifluoromethyl, SRb, SORb, SO2Rb, ORb, NRbRc, NRbCORc, NRbCOORC, COORb or CONRbRc, where Rb and Rc independently represent H, C1-6alkyl, phenyl or trifluoromethyl; and Z is O, S, NR8 or CR9R10, where R8 represents H, C1-6alkyl, phenyl, phenyl(C1-4alkyl), COR11, COOR11, CONR9R10 where R11 is phenyl, phenyl(C1-4alkyl) or C1-6alkyl, and R9 and R10 are each H, C1-6alkyl, phenyl or phenyl(C1-4alkyl); are tachykinin antagonists. They and their compositions are useful in medicine.
Merck Sharp & Dohme Limited
Swabey Ogilvy Renault
LandOfFree
Heterocyclic compounds, compositions containing them and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Heterocyclic compounds, compositions containing them and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heterocyclic compounds, compositions containing them and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1929270