Multivalent compounds for cross-linking receptors and uses...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 19/00 (2006.01) A61K 35/14 (2006.01) A61K 35/28 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) C07F 5/02 (2006.01) C07K 5/10 (2006.01) C07K 7/02 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/16 (2006.01) C07K 14/33 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/535 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2258038

Synthetic cross-linking homobivalent and heterobivalent compounds have been designed and developed. These compounds are low in molecular weight, have antagonistic or agonistic activity, and induce the association between two identical or similar natural receptors (homobivalent compounds) or induce the association between two different natural receptors (heterobivalent compounds).

L'invention concerne la conception et le développement de composés de réticulation synthétiques homobivalents ou hétérobivalents. Ces composés présentent un poids moléculaire peu élevé, une activité antagoniste ou agoniste, et provoquent une association entre deux récepteurs naturels identiques ou similaires (composés homobivalents) ou entre deux récepteurs naturels différents (composés hétérobivalents).

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