Methods for regulating neurotransmitter systems by inducing...

A - Human Necessities – 61 – K

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A61K 38/08 (2006.01) A61K 31/37 (2006.01) A61K 31/4178 (2006.01) A61K 31/439 (2006.01) A61K 31/496 (2006.01) A61K 31/5513 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2580694

The present invention relates to methods for regulating neurotransmitter systems by inducing a counteradaptation response. According to one embodiment of the invention, a method for regulating a neurotransmitter includes the step of repeatedly administering a ligand for a receptor in the neurotransmitter system, with a ratio of administration half-life to period between administrations of no greater than 1/2. The methods of the present invention may be used to address a whole host of undesirable mental and neurological conditions.

La présente invention se rapporte à des méthodes permettant de réguler les systèmes de neurotransmetteurs en induisant une réponse de contre-adaptation. Dans un mode de réalisation, une méthode permettant de réguler un neurotransmetteur comprend l'étape consistant à administrer de manière répétée un ligand destiné à un récepteur du système de neurotransmetteurs, le rapport entre la demi-vie d'administration et la période de temps séparant les administrations étant inférieur ou égal à ?. Les méthodes selon l'invention peuvent servir à lutter contre toute une série de troubles mentaux et neurologiques indésirables.

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