Bicycloheteroaryl compounds as p2x7 modulators and uses thereof

Details Bicycloheteroaryl compounds as p2x7 modulators and uses thereof Bicycloheteroaryl compounds as p2x7 modulators and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 217/04 (2006.01)

Patent

CA 2602718

Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: (I) The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

L'invention concerne des composés bicyclohétéroaryle représentés par la formule I. Ces composés peuvent être préparés sous forme de compositions pharmaceutiques et peuvent être utilisés pour la prévention et le traitement de diverses affections chez des mammifères, tels que des humains, notamment la douleur, l'inflammation, les lésions traumatiques, etc.

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