Ortho-substituted benzoic acid derivates

Details Ortho-substituted benzoic acid derivates Ortho-substituted benzoic acid derivates

C - Chemistry, Metallurgy

07

C

C07C 317/32 (2006.01) A61K 31/16 (2006.01) A61K 31/275 (2006.01) A61K 31/395 (2006.01) C07C 279/22 (2006.01) C07C 311/16 (2006.01) C07C 311/17 (2006.01) C07C 311/47 (2006.01) C07C 317/44 (2006.01) C07C 317/46 (2006.01) C07C 317/48 (2006.01) C07D 295/26 (2006.01)

Patent

CA 2156959

Ortho-substituted benzoic acid derivatives of the formula I Image I, in which R1, R2 and R3 have the given meanings, and Q is guanidyl, and also their physiologically harmless salts, exhibit antiarrhythmic properties and act as inhibitors of the cellular Na+/H+ antiporter. In addition, the compounds of the formula I, in which R1 to R3 and also Q have the given meanings, are suitable for use as valuable intermediates for the preparation of medicaments, in particular of inhibitors of the cellular Na+/H+ antiporter.

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