Peptidomimetic compounds and preparation of biologically...

Details Peptidomimetic compounds and preparation of biologically... Peptidomimetic compounds and preparation of biologically...

C - Chemistry, Metallurgy

07

K

C07K 7/64 (2006.01) A61K 38/12 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07K 5/00 (2006.01)

Patent

CA 2599876

The invention relates to novel cyclic peptidomimetic compounds containing the sequence RGD for the preparation of appropriately functionalised antagonists of .alpha.v.beta.3 and .alpha.v.beta.5 integrins, and intended, for example, for the treatment of altered angiogenic phenomena or for the preparation of diagnostically useful compounds.

La présente invention a trait à de nouveaux composés peptidomimétiques cycliques contenant la séquence RGD pour la préparation d'antagonistes fonctionnalisés de manière appropriée d'intégrines .alpha..nu..beta.3 et .alpha..nu..beta.5, et destinés, par exemple, au traitement de phénomènes angiogéniques altérés ou pour la préparation de composés utiles dans le diagnostic.

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