Substituted oxadiazolidinediones as pai-1 inhibitors

Details Substituted oxadiazolidinediones as pai-1 inhibitors Substituted oxadiazolidinediones as pai-1 inhibitors

A - Human Necessities

61

K

A61K 31/4245 (2006.01) A61P 7/02 (2006.01) C07D 413/06 (2006.01)

Patent

CA 2538353

The present invention relates generally to substituted oxadiazolidinediones of formula: (I) and methods of using them as inhibitors to modulate PAI-1 expression or activity in order to treat disorders associated with elevated PAI-1 levels.

L'invention concerne en général des oxadiazolidinediones substituées de formule générale (I) et des procédés d'utilisation de celles-ci en tant qu'inhibiteurs pour moduler l'expression ou l'activité du PAI-1 afin de traiter des troubles associés à des taux élevés de PAI-1.

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