Lipoxins and their stable analogs in the treatment of asthma...

Details Lipoxins and their stable analogs in the treatment of asthma... Lipoxins and their stable analogs in the treatment of asthma...

A - Human Necessities

61

K

A61K 31/202 (2006.01) A61K 31/232 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2465117

The use of lipoxin analogs for the treatment or prevention of asthma and asthma related diseases is described. In particular, acetylenic lipoxin analogs are effective for the treatment and prevention of eosinophil recruitment involved with the inflammation processes associated with asthma, asthma like conditions, and lung injuries associated from airway inflammation or infection as brought about by leukocyte-mediated injury from within.

L'invention concerne l'utilisation d'analogues de lipoxine dans le traitement ou la prévention de l'asthme et de maladies associées à l'asthme. Elle concerne, en particulier, des analogues acétyléniques de lipoxine efficaces dans le traitement et la prévention du recrutement de polynucléaires éosinophiles intervenant dans les processus d'inflammation associés à l'asthme, à des troubles similaires à l'asthme, et dans le traitement ou la prévention de lésions pulmonaires, associés à l'infection ou à l'inflammation des voies respiratoires causées de l'intérieur par des lésions dont la médiation est assurée par les leucocytes.

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