Substituted quinoxalin-2(1h)-ones useful as hiv reverse...

Details Substituted quinoxalin-2(1h)-ones useful as hiv reverse... Substituted quinoxalin-2(1h)-ones useful as hiv reverse...

C - Chemistry, Metallurgy

07

D

C07D 241/44 (2006.01) A61K 31/495 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2334332

The present invention relates to quinoxalin-2(1H)-ones of formula (I) or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same and methods of using the same for treating viral infection or as an assay standard or reagent.

Cette invention concerne des quinoxalin-2(1H)-ones qui correspondent à la formule (I), ainsi leurs formes ou leurs mélanges stéréoisomères et leurs sels pharmaceutiquement acceptables. Ces quinoxalin-2(1H)-ones peuvent être utilisés comme inhibiteurs de transcriptase inverse du VIH. Cette invention concerne également des compositions pharmaceutiques et des trousses de diagnostic comprenant ces quinoxalin-2(1H)-ones, ainsi que des procédés d'utilisation de ces derniers dans le traitement d'infections virales ou en qualité de standard d'analyse ou de réactif.

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