C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/32 (2006.01) C07C 27/06 (2006.01) C07C 27/08 (2006.01) C07C 69/675 (2006.01) C07D 315/00 (2006.01)
Patent
CA 2304809
Preparation of 4-hydroxy substituted butyrolactones is described. A process for the preparation of 3-hydroxybutyrolactone, 1,2,4-trihydroxybutane and 3,4-dihydroxy acid methyl ester from malic acid is particularly described. The preparation of 4-hydroxymethyl-4-hydroxybutyric acid-1-methyl ester and 4-hydroxymethyl butyrolactone is particularly described. The compounds are interme- diates to various pharmaceutical and agricultural products.
L'invention concerne la préparation de butyrolactones à substitution 4-hydroxy. L'invention concerne notamment un procédé de préparation de 3-hydroxybutyrolactone, 1,2,4-trihydroxybutane et d'ester méthylique d'acide 3,4-dihydroxy à partir d'acide malique. L'invention concerne notamment la préparation d'ester -1-méthylique d'acide 4-hydroxyméthyl-4-hydroxybutyrique et de butyrolactone de 4-hydroxyméthyle. Les composés constituent des intermédiaires dans divers produits pharmaceutiques et agricoles.
Macrae & Co.
Michigan State University
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